Research Associate - Translational Research

Country: Switzerland;

City: Basel

Vacancy added: 02.10.2019

Employer: University of Basel

Resumes due: 31.10.2019

 

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking an experienced and highly motivated Research Associate to join the Translation Group and conduct a transla-tional gene therapy project for vision loss.

IOB is a research institute combining basic and clinical research. Its mission is to drive innova-tions in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged and your knowledge expanded.

 

The main goal of the Translational Group is to develop and bring new classes of therapies to the clinic. We specifically focus on gene therapy and base editing technologies to provide treatments for genetic vision loss. Our activities include performing proof-of-concept studies in cells, organoids, retinal explants and animal models, optimizing lead candidate therapeutic agents, perform safety and biodistribution studies, characterize and recruit patients for the clinical trials, develop clinical outcome measures and prepare for regulatory authorization.


Your position

  • Design and conduct proof-of-concept gene therapy experiments in cell lines, retinal or-ganoids, retina explants and rodents
  • Develop and optimize methodologies to assay gene transfer to the retina
  • Interpret data from experiments and participate on research meetings

 

Your profile

  • Master's Degree or PhD degree in molecular biology or related field
  • Minimum 5 years experience in one of the following fields: translational neuroscience, gene therapy, molecular biology, vision research
  • Experience with the following techniques: molecular biology, histology, fluorescent mi-croscopy, confocal microscopy, Western-blotting, in vivo assays
  • Independence in planning, conductance, analysis and troubleshooting complex experi-ments
  • Ability and willingness to work with rodents
  • The candidate should be highly organized, precise, detail-oriented and computer skilled
  • Good written and verbal communications skills
  • Fluency in oral and written English

 

We offer you

  • Highly competitive conditions in a dynamic and international research community in Basel
  • IOB is an equal-opportunity employer with family-friendly work policies

 

For further information, please visit our websitehttps://iob.ch/or contact Josephine Puttkammer (josephine.puttkammer@iob.ch / +41 79 852 75 32).

 
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