24th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids

Country: Sweden

City: Srockholm

Abstr. due: 24.04.2020

Dates: 23.08.20 — 27.08.20

Area Of Sciences: Chemistry; Biology;

Organizing comittee e-mail: irt2020@akademikonferens.se

Organizers: Karolinska Institutet&partners

 

The biannual International Round Table (IRT) meetings are the conferences with the most respectable pedigree in the field of oligonucleotides/nucleic acids and their components, having a continuous lineage since 1974. The 24th International Roundtable meeting will gather researchers to discuss recent developments in topics related to the chemistry, biology and medicine of nucleosides, nucleotides and oligonucleotides/nucleic acids. The meeting will bring together established scientists and younger investigators from academia and industry from around the world, including students and postdocs, to share observations and discoveries pertinent to nucleic acids and their components.

TOPICS expected to be covered during the IRT 2020

NUCLEOSIDE CHEMISTRY

Synthesis, modifications, methods, prebiotic chemistry

OLIGONUCLEOTIDE DESIGN AND CHEMISTRY

Synthesis, modifications, conjugates, labeling, capping, ON and guide RNA design

NUCLEOSIDE BIOACTIVITY

Prodrugs, antiviral and antibacterial nucleosides

OLIGONUCLEOTIDE/RNA BASED THERAPY

siRNA, mRNA, microRNA and antisense therapy, miRNA targeting, splice correction/switching, gene activation/editing and toxicity.

DELIVERY AND TARGETING OF NUCLEOSIDES AND OLIGONUCLEOTIDES

Cellular uptake-enhancing and tissue-targeting modifications and conjugates, intracellular trafficking, protein interaction.

APPLICATIONS OF NUCLEIC ACIDS BEYOND THERAPY

Nanotechnology, origami, diagnostics, biophysics of nucleic acids, mechanisms and reactions involving nucleic acid components

NUCLEIC ACIDS: STRUCTURE, RECOGNITION AND CLEAVAGE

Aptamers, ribozymes/DNAzymes, artificial nucleases, enzymology of nucleic acid processing, small molecule recognition of nucleic acids, CRISPR/Cas

Conference Web-Site: https://www.irt2020.se/