PhD position in Organic Chemistry

Страна: Швеция;

Дедлайн: 15.08.2016



Uppsala University is an international research university focused on the development of science and education. Our most important assets are all the individuals who with their curiosity and their dedication make Uppsala University one of Sweden’s most exciting work places. Uppsala University has 40,000 students, 7,000 employees and a turnover of SEK 6,5 billion.


The chemistry research at BMC focuses on areas such as catalysis, molecular recognition, structure and dynamics of complex molecular systems, and correlations between the presence of chemical compounds and biomolecules with effects on various disease states. Research in organic chemistry at BMC is in particular focused on method development in organic synthesis and on design, synthesis and characterization of functional molecules with applications in biomedicine and materials science.

We are looking for a graduate student in Chemistry with specialization in Organic Chemistry

Description of the project
Many novel drug targets, in particular protein-protein interactions, cannot be modulated with small drug-like molecules. Instead, compounds in a different chemical space, e.g. macrocycles and peptides, are required for such “difficult targets”. We have built a significant knowledge base on properties required for compounds to bind to difficult targets while also being cell permeable. The project aims to expand our knowledge by synthesis of macrocycles that have been designed to study key properties, such as their target binding affinity and cell permeability. It will be carried out in collaboration with AstraZenca R&D Gothenburg.

Appointment period
The PhD position is for four years, extendable to a maximum of five years by including department duties, typically teaching.

Nature of duties
The PhD student is expected to carry out advanced research in organic chemistry and to broaden his/her perspective and knowledge of organic chemistry by taking graduate courses in relevant subjects. The student is also expected to teach and participate in general departmental work, such as instrument maintenance, to a level corresponding to a maximum of 20% of the employment time. Since first year undergraduate courses are taught in Swedish, proficiency in Swedish may be considered an advantage.

To qualify for a PhD position the applicant must have at least 240 credits (hp), or an equivalent basic university education, with at least 90 credits in chemistry and 60 credits at the advanced level. At least 40 credits must be in organic chemistry at the advanced level. Applicants from outside the European Union must provide the results from a GRE general test.

It is desired that you have a science master´s degree in organic or medicinal chemistry, or similar experience. Strong knowledge in synthetic organic chemistry is required, and some experience in computational and/or medicinal chemistry is and advantage.

We place great emphasis on your personal qualifications. You need to have a strong motivation for the research project and to be able to contribute with creative ideas. This project requires that you are able to work independently, but that you also have excellent collaborative skills as the project will be run in close collaboration with scientists at AstraZeneca. You also need good language skills in English in order to be able to interact and publish internationally.

Criteria for ranking
The ranking of applicants will be based on undergraduate grades, on the undergraduate education profile and on any additional experience of research in areas of relevance for the research project. Such additional experience should be demonstrated, e.g. through articles published in international peer reviewed journals or by employments at companies or institutions active in the field of research. High emphasis will also be put on personal qualifications required for the project.

In filling this position, the university aims to recruit the person who, in a combined evaluation of competence, skills and documented qualifications, are judged most suitable to carry out and develop the project-in-hand and to contribute to a positive development of the department of chemistry. Interviews will be performed with the top candidates through visits to Uppsala University and/or AstraZeneca, or by electronic means.

Your application
Your application must include a personal letter with a short description of yourself and your specific areas of interest in research. You must also include a CV, authorized copies of degrees and diplomas, copies of your bachelor or master thesis and other documents, such as publications, that you want to invoke. Names and contact details of at least two scientists that have accepted to act as references for you must also be included.

Uppsala University aims for gender balance and diversity in all activities in order to achieve a higher quality at all levels of the organization. We therefore welcome applicants of any gender and with different birth background, functionality and life experience.

For further information about the position please contact:
Professor Jan Kihlberg (e-mail:

You are welcome to submit your application no later than 2016-08-15, UFV-PA 2016/2090.


We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.

Placement: Department of Chemistry - BMC

Type of employment: Full time , Temporary position longer than 6 months

Pay: Fixed pay

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Marie Ols, TCO/ST 018-471 2459
Per Sundman, Saco-rådet 018-471 1485
Stefan Djurström, Seko 018-471 3315

Number of reference: UFV-PA 2016/2090

Last application date: 2016-08-15