Synthesis and development of therapeutic transdermal drug delivery system

Schematic representation delivery of the drug from the patch into the skin

Components of a patch

Therapeutic transdermal  drug delivery systems (TTDDS) also known as “patches”. Transdermal patch is an alternative dosage form. It is  designed to deliver a therapeutically effective amount of drug across a patient’s skin.  TTDDS have many indisputable and obvious advantages over other dosage forms:

- The ability to provide more rapid drug effect

- Easy way to use

- Reducing the frequency of the appointment by delivering the required dose of the drug over a longer period of time.

Our Department can develop the composition of a transdermal patch for your active compound. We  can carry out all kind of physicochemical, analytical analyses of transdermal patch and,  of course,  write technical documentation (specifications, analytical methods of quality control, etc.)

The simplest form of TTDDS consists of the following components:

- Liner – Protects the patch during storage. The liner should be removed before use.

- Drug – Drug solution is in direct contact with the release liner.

- Adhesive – Holds the components of the patch together. It also helps to keep the patch ‘glued’ to the skin.

- Membrane – Controls the release of the drug from the patch.

- Backing – Protects the overall patch during the application period.

Developer: Chuiko Institute of Surface Chemistry (CISC) of National Academy of Sciences of Ukraine

Kyiv, Ukraine: Tel.: +38 (044) 422 96 27; Fax: +38 (044) 424 35 67; e-mail: [email protected]