Keystone Symposia: Immunity to Veterinary Pathogens – Informing Vaccine Development

Країна: США

Місто: Keystone

Тези до: 21.10.2014

Дати: 20.01.15 — 25.01.15

Область наук: Біологічні; Ветеринарні;

Е-мейл Оргкомітету:

Організатори: Keystone Symposia on Molecular & Cellular Biology



The need for more effective vaccines to protect food animals against infectious diseases has never been greater. Pressures on food sources are predicted to reach a critical state in a few decades resulting in food shortages, especially in the developing world. While there is a long history of using vaccination to control animal diseases, the most notable success being the eradication of rinderpest, there are many important diseases for which no effective vaccines are available. Advances in genomic technologies, coupled with improved knowledge of the cellular and molecular events involved in the immune response, provide exciting new opportunities for vaccine development. However, effective exploitation of these advances needs to be based on an understanding of the immune responses that mediate effective immunity against the target pathogens. While laboratory animal models have proved invaluable in elucidating fundamental immunological principles, the results of vaccination studies have often failed to translate to larger animal species and humans. Hence, there is a need to study the target diseases in their natural hosts. Animals also provide valuable experimental models for studies of zoonotic pathogens that cause disease in both animals and humans (e.g. TB and influenza), as well as closely related pathogens that cause similar diseases in animals and humans. This meeting seeks to highlight the value of studying immune responses to infectious disease in animals not only to develop control measures for animal diseases but also to advance knowledge that may be more widely applicable for vaccine development. Understanding the immune response in veterinary species holds the promise of accelerating vaccine development for food animals, companion pets and clearly humans, directly addressing the One World, One Health concept emerging in vaccine research.

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