Cellular synapsis for cell-cell signalling

Країна: Іспанія

Місто: Madrid

Тези до: 15.04.2015

Дати: 26.05.15 — 29.05.15

Область наук: Біологічні;

Е-мейл Оргкомітету: embo.workshop.2015@cbm.csic.es

Організатори: EMBO

 

Whereas it has long been assumed that signalling proteins function as classic paracrine factors and that synaptic signalling between distant cells is characteristic only of neurons, recent progress in the field of morphogen signalling provides evidence of an alternative model. Work principally in Drosophila, but also in chick, zebrafish, sea urchin and frog, shows that morphogen signalling in many contexts is mediated by specialized filopodia (“cytonemes”) that reach across long distances to transport signals at sites of contact between producing and target cells. These observations suggest that exchange of signals at synapses could be an unanticipated general mechanism of paracrine signalling.

The objective of this EMBO Workshop is to bring together researchers who study morphogen signalling, filopodia formation and dynamics, axon guidance and neuronal signalling, exosomes, nanotubes and wavefront-engineering microscopy. This mix of topics and interests, which all pertain to synaptic signalling by neuronal and non-neuronal cells, has not previously been understood to be functionally related, but a workshop that brings them together promises to be an exciting opportunity for cross-fertilization.

 

Веб-сторінка конференції: http://events.embo.org/15-cell-cell/