The Landscape of Genetic Variants in Asian Founder Populations

Країна: Індія

Місто: Kochi

Тези до: 09.11.2017

Дати: 09.11.17 — 12.11.17

Область наук: Біологічні;

Е-мейл Оргкомітету:

Організатори: Conference Secretariat


Disease occurrence and disease control measures such as prevention and treatment are dictated by the genetic composition of the individual and the genetic/molecular make-up of the population from which the individual stems. The world has evidenced massive population movements over thousands of years. As a consequence genetic heterogeneity, through selection processes, has developed and populations have acquired not only social, behavioral and cultural characteristics and beliefs, but also biological fingerprints unifying members of these populations.


Our current conference, second in the series on founder populations, is aimed at identifying the historical origins of the many different Asian populations, their biological uniqueness and its association with disease patterns of the local populations. Understanding population genetics and genetic variation will allow us to bridge the gap in the translation of our knowledge from populations to individuals and to provide medical services which are tailored to the biological composition of these populations.


Our conference will thus deal with history and genetics, with genetic syndromes of specific populations, with metabolic/molecular markers of disease risk and response to medical interventions in complex diseases such as cardiovascular diseases, diabetes and malignant diseases. We will examine cultural and religious influences on incorporating genetic knowledge as a means of improving our combat with diseases.


The first conference in this series was centered on knowledge acquired from the Jewish population. This ancient population stemming from the Middle-East formed a unique natural example of a population with strong genetic internal resemblance, yielding many founder effects in various common diseases, coupled with a religious legend of ethical approaches towards biology and health. It is a classic example of how the experience of a specific population can serve as a model for learning for other populations. Jews themselves originated in the Asian Near East and migrated to many other areas in Asia, establishing significant communities on the Indian sub-continent, specifically the Bene-Israel Jews who lived mainly in the Mumbai area and the Kochini Jews from Kochi, Kerala where the second founder populations conference will be held.


Before we can actually achieve effective personalized health care we need to first understand the genomic origins of the populations we treat, learn how they differ between populations, and discover from other populations how they culturally refer to and recruit genetics for cure.


We invite you all to attend this unique, multidisciplinary, out of the box conference for a comprehensive learning experience of the genetic variability of Asian populations associated with pre-historical and historical events, and how to harness this knowledge for better health for all.

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